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Chemical structure of MSC-4106

GC65993

MSC-4106

Also known as 2-methyl-4-[4-(trifluoromethyl)phenyl]pyrazolo[3,4-b]indole-7-carboxylic acid

MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD· MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model

ChemicalCAS2738542-58-8MW359.3FormulaC18H12F3N3O2
CAS number
2738542-58-8
Molecular weight
359.3
Formula
C18H12F3N3O2
Solubility
DMSO : 250 mg/mL (695·80 mM; Need ultrasonic)
InChIKey
HUSMWXZHQVTDRU-UHFFFAOYSA-N
Catalogue number
GC65993
Brand
GLPBIO
Computed properties PubChem CID 157037366 · XLogP 4.1 · TPSA 60.1 Ų · H-bond donors 1
XLogP
4.1
TPSA
60.1 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
26

SMILES CN1C=C2C3=C(C=CC(=C3)C(=O)O)N(C2=N1)C4=CC=C(C=C4)C(F)(F)F

Computed descriptors from PubChem (CID 157037366), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.