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Chemical structure of IDO1/TDO-IN-4

GC69256

IDO1/TDO-IN-4

Also known as 1-(1H-imidazol-5-yl)-9H-pyrido[3,4-b]indole

IDO1/TDO-IN-4 is an effective IDO1/TDO dual inhibitor with IC50 values of 3·53 μM (IDO1) and 1·15 μM (TDO)· IDO1/TDO-IN-4 can form hydrogen bonds with IDO1 and undergoes π-π stacking interactions with TDO· It can be used for research on depression, infectious diseases caused by depression, metabolic diseases, and autoimmune diseases

ChemicalCAS461424-21-5MW234.26FormulaC14H10N4
CAS number
461424-21-5
Molecular weight
234.26
Formula
C14H10N4
Solubility
DMSO ： 125 mg/mL (533·60 mM; ultrasonic and warming and heat to 60°C)
InChIKey
HUTBKGSJEGKJBG-UHFFFAOYSA-N
Catalogue number
GC69256
Brand
GLPBIO
Computed properties PubChem CID 44269517 · XLogP 2.2 · TPSA 57.4 Ų · H-bond donors 2
XLogP
2.2
TPSA
57.4 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
18

SMILES C1=CC=C2C(=C1)C3=C(N2)C(=NC=C3)C4=CN=CN4

Computed descriptors from PubChem (CID 44269517), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.