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Chemical structure of IDO1/2-IN-1 hydrochloride

GC65499

IDO1/2-IN-1 hydrochloride

Also known as N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-[4-(2-hydroxyethoxymethyl)triazol-1-yl]ethylamino]-1,2,5-oxadiazole-3-carboximidamide;hydrochloride

IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively· IDO1/2-IN-1 hydrochloride exhibits antitumor activies· Orally active

ChemicalCAS2310286-60-1MW521.73FormulaC16H19BrClFN8O4
CAS number
2310286-60-1
Molecular weight
521.73
Formula
C16H19BrClFN8O4
InChIKey
OFKAFAFCZQUHPC-UHFFFAOYSA-N
Catalogue number
GC65499
Brand
GLPBIO
Computed properties PubChem CID 141755880 · TPSA 156 Ų · H-bond donors 5 · H-bond acceptors 11
TPSA
156 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
11
Heavy atoms
31

SMILES C1=CC(=C(C=C1N=C(C2=NON=C2NCCN3C=C(N=N3)COCCO)NO)Br)F.Cl

Computed descriptors from PubChem (CID 141755880), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.