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Chemical structure of GSK761

GC69197

GSK761

GSK761 is a selective inhibitor of the SP140 nuclear protein (SP140), with an IC50 value of 77·79 nM· GSK761 reduces the differentiation of monocytes into inflammatory macrophages and LPS-induced inflammatory activation· GSK761 induces the production of CD206+ regulatory macrophages by inhibiting SP140

ChemicalMW646.82FormulaC40H46N4O4
CAS number
—
Molecular weight
646.82
Formula
C40H46N4O4
Solubility
DMSO ： 125 mg/mL (193·25 mM; ultrasonic and warming and heat to 60°C)
Catalogue number
GC69197
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.