GC62654
GSK778
Also known as 4-[2-(methoxymethyl)-1-[(1R)-1-phenylethyl]-8-[[(3S)-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole
GSK778 (iBET-BD1) is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively
ChemicalCAS2451862-42-1MW511.61FormulaC30H33N5O3
- CAS number
- 2451862-42-1
- Molecular weight
- 511.61
- Formula
- C30H33N5O3
- Solubility
- DMSO ： 41·67 mg/mL (81·45 mM; Need ultrasonic)
- InChIKey
- ZORLJXWXFABTPZ-CTNGQTDRSA-N
- Catalogue number
- GC62654
- Brand
- GLPBIO
Computed properties PubChem CID 146018691 · XLogP 4.2 · TPSA 87.2 Ų · H-bond donors 1
- XLogP
- 4.2
- TPSA
- 87.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 38
SMILES CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=N4)COC)[C@H](C)C5=CC=CC=C5)OC[C@H]6CCNC6
Computed descriptors from PubChem (CID 146018691), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il