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Chemical structure of GLP-1R modulator C5

GC69167

GLP-1R modulator C5

Also known as 3-hydroxy-3-phenacyl-1-(2-phenylethyl)indol-2-one

GLP-1R modulator C5 is a conformational regulator that enhances the binding of GLP-1 to GLP-1R through a transmembrane site (EC50 1·59 ± 0·53 μM)

ChemicalCAS421578-93-0MW371.43FormulaC24H21NO3
CAS number
421578-93-0
Molecular weight
371.43
Formula
C24H21NO3
Solubility
DMSO : 50 mg/mL (134·61 mM; Need ultrasonic)
InChIKey
QSAOBVACSHPJMW-UHFFFAOYSA-N
Catalogue number
GC69167
Brand
GLPBIO
Computed properties PubChem CID 3967615 · XLogP 4 · TPSA 57.6 Ų · H-bond donors 1
XLogP
4
TPSA
57.6 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
28

SMILES C1=CC=C(C=C1)CCN2C3=CC=CC=C3C(C2=O)(CC(=O)C4=CC=CC=C4)O

Computed descriptors from PubChem (CID 3967615), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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