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Chemical structure of GLP-1R modulator C16

GC69166

GLP-1R modulator C16

Also known as N-[[4-[(2-chloro-6-fluorophenyl)methoxy]-3-methoxyphenyl]methyl]-2-morpholin-4-ylethanamine

GLP-1R modulator C16 is a conformational regulator that enhances the binding of GLP-1 to GLP-1R through a transmembrane site (EC50 8·43 ± 3·82 μM)

ChemicalCAS875005-43-9MW408.89FormulaC21H26ClFN2O3
CAS number
875005-43-9
Molecular weight
408.89
Formula
C21H26ClFN2O3
Solubility
DMSO : 50 mg/mL (122·28 mM; ultrasonic and warming and heat to 60°C)
InChIKey
PQAPAXXUERVALT-UHFFFAOYSA-N
Catalogue number
GC69166
Brand
GLPBIO
Computed properties PubChem CID 3162206 · XLogP 3.1 · TPSA 43 Ų · H-bond donors 1
XLogP
3.1
TPSA
43 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
28

SMILES COC1=C(C=CC(=C1)CNCCN2CCOCC2)OCC3=C(C=CC=C3Cl)F

Computed descriptors from PubChem (CID 3162206), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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