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Chemical structure of GL0388

GC69163

GL0388

Also known as 2-[[3-[(E)-(2-fluorofluoren-9-ylidene)methyl]-2-pyridinyl]oxy]ethanamine

GL0388 is a Bax activator that induces the insertion of Bax into mitochondrial membranes· GL0388 exhibits anti-proliferative activity against various cancer cells with IC50 values ranging from 0·299-1·57 μM· GL0388 activates Bax and induces Bax-mediated apoptosis in cells· In vivo, GL0388 inhibits the growth of xenograft tumors in breast cancer

ChemicalCAS2886772-68-3MW332.37FormulaC21H17FN2O
CAS number
2886772-68-3
Molecular weight
332.37
Formula
C21H17FN2O
InChIKey
WCVGRSPKTHQNCR-XDHOZWIPSA-N
Catalogue number
GC69163
Brand
GLPBIO
Computed properties PubChem CID 162640853 · XLogP 3.5 · TPSA 48.1 Ų · H-bond donors 1
XLogP
3.5
TPSA
48.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
25

SMILES C1=CC=C\2C(=C1)C3=C(/C2=C/C4=C(N=CC=C4)OCCN)C=C(C=C3)F

Computed descriptors from PubChem (CID 162640853), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.