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Chemical structure of GKT136901 hydrochloride

GC62989

GKT136901 hydrochloride

Also known as 2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6-dione;hydrochloride

GKT136901 hydrochloride is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively

ChemicalCAS1254507-01-1MW403.26FormulaC19H16Cl2N4O2
CAS number
1254507-01-1
Molecular weight
403.26
Formula
C19H16Cl2N4O2
Solubility
DMSO ： 62·5 mg/mL (154·99 mM; Need ultrasonic)|Water ： 4 mg/mL (9·92 mM; ultrasonic and warming and heat to 60°C)
InChIKey
BIXDBKGUQPCHLH-UHFFFAOYSA-N
Catalogue number
GC62989
Brand
GLPBIO
Computed properties PubChem CID 155977664 · TPSA 65.5 Ų · H-bond donors 2 · H-bond acceptors 4
TPSA
65.5 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
27

SMILES CC1=C2C(=CC(=O)N1CC3=CC=CC=N3)NN(C2=O)C4=CC=CC=C4Cl.Cl

Computed descriptors from PubChem (CID 155977664), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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