Loading...
Chemical structure of ERAP2-IN-1

GC69078

ERAP2-IN-1

Also known as 4-methoxy-3-[[2-piperidin-1-yl-4-(trifluoromethyl)phenyl]sulfamoyl]benzoic acid

ERAP2-IN-1 (compound 61) is a non-competitive inhibitor of ERAP2· It specifically inhibits the peptide hydrolysis activity of ERAP2, with an inhibition activity of IC50 = 27 μM for Arg-AMC hydrolysis and IC50 = 44 μM for model peptide hydrolysis

ChemicalCAS2420551-38-6MW458.45FormulaC20H21F3N2O5S
CAS number
2420551-38-6
Molecular weight
458.45
Formula
C20H21F3N2O5S
Solubility
DMSO ： 250 mg/mL (545·32 mM; Need ultrasonic)
InChIKey
BGLAMEXMBJAJBI-UHFFFAOYSA-N
Catalogue number
GC69078
Brand
GLPBIO
Computed properties PubChem CID 85470736 · XLogP 3.8 · TPSA 104 Ų · H-bond donors 2
XLogP
3.8
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
31

SMILES COC1=C(C=C(C=C1)C(=O)O)S(=O)(=O)NC2=C(C=C(C=C2)C(F)(F)F)N3CCCCC3

Computed descriptors from PubChem (CID 85470736), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.