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Chemical structure of ERB 041

GC10389

ERB 041

Also known as 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol

ERB 041 (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5·4, 3·1 and 3·7 nM for human, rat and mouse ERβ, respectively· ERB 041 displays >200-fold selectivity for ERβ over ERα· ERB 041 is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway· ERB 041 induces ovarian cancer apoptosis

ChemicalCAS524684-52-4MW271.24FormulaC15H10FNO3
CAS number
524684-52-4
Molecular weight
271.24
Formula
C15H10FNO3
Solubility
DMSO: 25 mg/ml
InChIKey
MQIMZDXIAHJKQP-UHFFFAOYSA-N
Catalogue number
GC10389
Brand
GLPBIO
Computed properties PubChem CID 656954 · XLogP 3.6 · TPSA 66.5 Ų · H-bond donors 2
XLogP
3.6
TPSA
66.5 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
20

SMILES C=CC1=C2C(=CC(=C1)O)N=C(O2)C3=CC(=C(C=C3)O)F

Computed descriptors from PubChem (CID 656954), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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