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Chemical structure of EIF2α activator 2

GC69047

EIF2α activator 2

Also known as 1-[4-[4-(trifluoromethyl)phenoxy]cyclohexyl]-3-[3-(trifluoromethyl)phenyl]urea

EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2α (eIF2α) phosphorylation· In SRB cell proliferation assays, the IC50 is 0·46 μM· EIF2α activator 2 also exhibits anti-proliferative activity against K562 and PBMC cells with IC50 values of 4·79 and 10·52 μM, respectively

ChemicalCAS1501618-04-7MW446.39FormulaC21H20F6N2O2
CAS number
1501618-04-7
Molecular weight
446.39
Formula
C21H20F6N2O2
Solubility
DMSO ： 250 mg/mL (560·05 mM; Need ultrasonic)
InChIKey
MFRDVPYKJUYMDN-UHFFFAOYSA-N
Catalogue number
GC69047
Brand
GLPBIO
Computed properties PubChem CID 72793091 · XLogP 5.7 · TPSA 50.4 Ų · H-bond donors 2
XLogP
5.7
TPSA
50.4 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
31

SMILES C1CC(CCC1NC(=O)NC2=CC=CC(=C2)C(F)(F)F)OC3=CC=C(C=C3)C(F)(F)F

Computed descriptors from PubChem (CID 72793091), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.