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Chemical structure of Dot1L-IN-1 TFA

GC69002

Dot1L-IN-1 TFA

Dot1L-IN-1 TFA is a highly efficient and selective Dot1L inhibitor with a Ki of 2 pM and IC50<0·1 nM· Dot1L-IN-1 TFA effectively inhibits H3K79 dimethylation in HeLa cells (IC50=3 nM) as well as the activity of the HoxA9 promoter in Molm-13 cells (IC50=17 nM)

ChemicalMW760.23FormulaC34H37ClF3N9O4S
CAS number
Molecular weight
760.23
Formula
C34H37ClF3N9O4S
Solubility
DMSO : 50 mg/mL (65·77 mM; Need ultrasonic)
Catalogue number
GC69002
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.