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Chemical structure of CM03

GC68887

CM03

Also known as 14-hydroxy-6,13-bis(3-morpholin-4-ylpropyl)-10-(2-pyrrolidin-1-ylethylimino)-6,13-diazatetracyclo[6.6.2.04,16.011,15]hexadeca-1(14),2,4(16),8,11(15)-pentaene-5,7,12-trione

CM03 is an effective DNA G-quadruplex (G4s) binding molecule· CM03 can stabilize G4s, downregulate more genes containing G4s, and increase the incidence of double-stranded break events (DSBs) caused by DNA and chromatin structural torsion strain· CM03 has selective effects on pancreatic cancer cells

ChemicalCAS2101208-44-8MW632.75FormulaC34H44N6O6
CAS number
2101208-44-8
Molecular weight
632.75
Formula
C34H44N6O6
Solubility
DMSO ： 2 mg/mL (3·16 mM; ultrasonic and warming and heat to 60°C)
InChIKey
WHLXIQNGOLIDJQ-UHFFFAOYSA-N
Catalogue number
GC68887
Brand
GLPBIO
Computed properties PubChem CID 137203116 · XLogP -0.5 · TPSA 118 Ų · H-bond donors 1
XLogP
-0.5
TPSA
118 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
46

SMILES C1CCN(C1)CCN=C2C=C3C4=C(C=CC5=C(N(C(=O)C2=C54)CCCN6CCOCC6)O)C(=O)N(C3=O)CCCN7CCOCC7

Computed descriptors from PubChem (CID 137203116), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.