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Chemical structure of PROTAC BRAF-V600E degrader-1

GC68289

PROTAC BRAF-V600E degrader-1

Also known as N-[3-[5-[[1-[3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoyl]piperidin-4-yl]-methylamino]-3-pyrimidin-5-ylpyrrolo[3,2-b]pyridin-1-yl]-2,4-difluorophenyl]propane-1-sulfonamide

PROTAC BRAF-V600E degrader-1 (catalogue number GC68289) is a research-grade chemical available from LABO Scientific in Israel, CAS registry number 2417296-84-3. Molecular formula C48H54F2N10O10S, molecular weight 1001.07. IUPAC name: N-[3-[5-[[1-[3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoyl]piperidin-4-yl]-methylamino]-3-pyrimidin-5-ylpyrrolo[3,2-b]pyridin-1-yl]-2,4-difluorophenyl]propane-1-sulfonamide. Supplied as 5mg at ₪2,349.46; the final price is confirmed on your quote, and the lot certificate of analysis and safety data sheet are emailed with your order confirmation.

ChemicalCAS2417296-84-3MW1001.07FormulaC48H54F2N10O10S
CAS number
2417296-84-3
Molecular weight
1001.07
Formula
C48H54F2N10O10S
InChIKey
FMUGAZVOOIUFAT-UHFFFAOYSA-N
Catalogue number
GC68289
Brand
GLPBIO
Computed properties PubChem CID 146161288 · XLogP 3.1 · TPSA 245 Ų · H-bond donors 3
XLogP
3.1
TPSA
245 Ų
H-bond donors
3
H-bond acceptors
18
Rotatable bonds
22
Heavy atoms
71

SMILES CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)N2C=C(C3=C2C=CC(=N3)N(C)C4CCN(CC4)C(=O)CCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CN=CN=C8)F

Computed descriptors from PubChem (CID 146161288), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.