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Chemical structure of Thalidomide-PEG4-NH2 hydrochloride

GC67507

Thalidomide-PEG4-NH2 hydrochloride

Also known as 4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

Thalidomide-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology

ChemicalCAS2387510-82-7MW485.92FormulaC21H28ClN3O8
CAS number
2387510-82-7
Molecular weight
485.92
Formula
C21H28ClN3O8
InChIKey
NDHMOOQETYCWFG-UHFFFAOYSA-N
Catalogue number
GC67507
Brand
GLPBIO
Computed properties PubChem CID 146018962 · TPSA 146 Ų · H-bond donors 3 · H-bond acceptors 9
TPSA
146 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
13
Heavy atoms
33

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCOCCOCCOCCN.Cl

Computed descriptors from PubChem (CID 146018962), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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