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Chemical structure of TCO-PEG12-NHS ester

GC67491

TCO-PEG12-NHS ester

Also known as (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[(4Z)-cyclooct-4-en-1-yl]oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs· TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS2185016-39-9MW866.99FormulaC40H70N2O18
CAS number
2185016-39-9
Molecular weight
866.99
Formula
C40H70N2O18
InChIKey
NVOXZBGFZZFRHC-UPHRSURJSA-N
Catalogue number
GC67491
Brand
GLPBIO
Computed properties PubChem CID 146026014 · XLogP -0.6 · TPSA 213 Ų · H-bond donors 1
XLogP
-0.6
TPSA
213 Ų
H-bond donors
1
H-bond acceptors
18
Rotatable bonds
43
Heavy atoms
60

SMILES C1C/C=C\CCC(C1)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O

Computed descriptors from PubChem (CID 146026014), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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