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Chemical structure of TCO-NHS ester

GC39607

TCO-NHS ester

Also known as [(4E)-cyclooct-4-en-1-yl] (2,5-dioxopyrrolidin-1-yl) carbonate

TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS1191901-33-3MW267.28FormulaC13H17NO5
CAS number
1191901-33-3
Molecular weight
267.28
Formula
C13H17NO5
Solubility
Soluble in DMSO
InChIKey
OUGQJOKGFAIFAQ-OWOJBTEDSA-N
Catalogue number
GC39607
Brand
GLPBIO
Computed properties PubChem CID 58490201 · XLogP 1.9 · TPSA 72.9 Ų · H-bond donors 0
XLogP
1.9
TPSA
72.9 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
19

SMILES C1C/C=C/CCC(C1)OC(=O)ON2C(=O)CCC2=O

Computed descriptors from PubChem (CID 58490201), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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