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Chemical structure of Thalidomide-PEG2-C2-NH2

GC66644

Thalidomide-PEG2-C2-NH2

Also known as 4-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Thalidomide-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology

ChemicalCAS2093416-32-9MW404.42FormulaC19H24N4O6
CAS number
2093416-32-9
Molecular weight
404.42
Formula
C19H24N4O6
InChIKey
KFHRVSOIOPAUND-UHFFFAOYSA-N
Catalogue number
GC66644
Brand
GLPBIO
Computed properties PubChem CID 131988632 · XLogP -0.4 · TPSA 140 Ų · H-bond donors 3
XLogP
-0.4
TPSA
140 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
29

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCN

Computed descriptors from PubChem (CID 131988632), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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