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Chemical structure of LDC4297 hydrochloride

GC66446

LDC4297 hydrochloride

Also known as 2-piperidin-3-yloxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine;hydrochloride

LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0·13 nM· LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24·5 nM· LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 values of 0·02-1·21 μM· LDC4297 hydrochloride can be used for the research of infection

ChemicalCAS2319747-14-1MW468.98FormulaC23H29ClN8O
CAS number
2319747-14-1
Molecular weight
468.98
Formula
C23H29ClN8O
InChIKey
CEUJJAKJRBKKSL-UHFFFAOYSA-N
Catalogue number
GC66446
Brand
GLPBIO
Computed properties PubChem CID 137958370 · TPSA 94.2 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
94.2 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
33

SMILES CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3N4C=CC=N4)OC5CCCNC5.Cl

Computed descriptors from PubChem (CID 137958370), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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