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Chemical structure of LDC4297

GC19219

LDC4297

Also known as 2-piperidin-3-yloxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine

LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0·13 nM

ChemicalCAS1453834-21-3MW432.52FormulaC23H28N8O
CAS number
1453834-21-3
Molecular weight
432.52
Formula
C23H28N8O
Solubility
DMSO : ≥ 60 mg/mL (138·72 mM)
InChIKey
LSGRZENCFIIHNV-UHFFFAOYSA-N
Catalogue number
GC19219
Brand
GLPBIO
Computed properties PubChem CID 78161839 · XLogP 3.4 · TPSA 94.2 Ų · H-bond donors 2
XLogP
3.4
TPSA
94.2 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
32

SMILES CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3N4C=CC=N4)OC5CCCNC5

Computed descriptors from PubChem (CID 78161839), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.