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Chemical structure of AFM-30a hydrochloride

GC66379

AFM-30a hydrochloride

AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity· AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9·5 μM· AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0·4 μM· AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis

ChemicalMW502.97FormulaC24H28ClFN6O3
CAS number
Molecular weight
502.97
Formula
C24H28ClFN6O3
Solubility
H2O : 50 mg/mL (99·41 mM; Need ultrasonic); DMSO : 50 mg/mL (99·41 mM; ultrasonic and warming and heat to 60°C)
Catalogue number
GC66379
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.