GC66054
Nrf2 activator-4
Also known as (E)-1-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]phenyl]-3-[2-(trifluoromethyl)phenyl]prop-2-en-1-one;hydrochloride
Nrf2 activator-4 (Compound 20a) is a highly potent, orally active Nrf2 activator with an EC50 of 0·63 μM· Nrf2 activator-4 suppresses reactive oxygen species against oxidative stress in microglia· Nrf2 activator-4 effectively recovers the learning and memory impairment in a scopolamine-induced mouse model
ChemicalCAS2383016-68-8MW468.9FormulaC23H24ClF3N2O3
- CAS number
- 2383016-68-8
- Molecular weight
- 468.9
- Formula
- C23H24ClF3N2O3
- Solubility
- DMSO ： 100 mg/mL (213·27 mM; Need ultrasonic)
- InChIKey
- MLBFDNAGDZEBHA-YGCVIUNWSA-N
- Catalogue number
- GC66054
- Brand
- GLPBIO
Computed properties PubChem CID 155527528 · TPSA 49.9 Ų · H-bond donors 1 · H-bond acceptors 7
- TPSA
- 49.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 32
SMILES CN1CCN(CC1)C(=O)COC2=CC=C(C=C2)C(=O)/C=C/C3=CC=CC=C3C(F)(F)F.Cl
Computed descriptors from PubChem (CID 155527528), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il