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Chemical structure of B-Raf IN 10

GC65978

B-Raf IN 10

Also known as N-[2,4,5-trifluoro-3-(3-morpholin-4-ylquinoxaline-6-carbonyl)phenyl]propane-1-sulfonamide

B-Raf IN 10 (Compound C09) is a BRAF inhibitor with an IC50 between 50 and 100 nM· B-Raf IN 10 shows antitumor activity

ChemicalCAS1425485-87-5MW494.49FormulaC22H21F3N4O4S
CAS number
1425485-87-5
Molecular weight
494.49
Formula
C22H21F3N4O4S
Solubility
DMSO ： 100 mg/mL (202·23 mM; ultrasonic and warming and heat to 60°C)
InChIKey
HAYBWDINAFTFCJ-UHFFFAOYSA-N
Catalogue number
GC65978
Brand
GLPBIO
Computed properties PubChem CID 71506198 · XLogP 2.8 · TPSA 110 Ų · H-bond donors 1
XLogP
2.8
TPSA
110 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
34

SMILES CCCS(=O)(=O)NC1=CC(=C(C(=C1F)C(=O)C2=CC3=NC(=CN=C3C=C2)N4CCOCC4)F)F

Computed descriptors from PubChem (CID 71506198), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.