GC11599
B-Raf inhibitor 1
Also known as 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)-2-pyridinyl]isoquinoline-1,5-diamine
B-Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0·3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively
ChemicalCAS1093100-40-3MW478.94FormulaC26H19ClN8
- CAS number
- 1093100-40-3
- Molecular weight
- 478.94
- Formula
- C26H19ClN8
- Solubility
- ≥ 47·9mg/mL in DMSO
- InChIKey
- KKVYYGGCHJGEFJ-UHFFFAOYSA-N
- Catalogue number
- GC11599
- Brand
- GLPBIO
Computed properties PubChem CID 44223999 · XLogP 5.6 · TPSA 104 Ų · H-bond donors 3
- XLogP
- 5.6
- TPSA
- 104 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 5
- Heavy atoms
- 35
SMILES CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6
Computed descriptors from PubChem (CID 44223999), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il