GC65905
NBD-14189
Also known as N-[(1S)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-[3-fluoro-4-(trifluoromethyl)phenyl]-1H-pyrrole-2-carboxamide
NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus· NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50＜200 nM)
ChemicalCAS2234273-72-2MW428.4FormulaC18H16F4N4O2S
- CAS number
- 2234273-72-2
- Molecular weight
- 428.4
- Formula
- C18H16F4N4O2S
- Solubility
- DMSO ： 100 mg/mL (233·43 mM; Need ultrasonic)
- InChIKey
- ZKOITYDZLQYLNI-HNNXBMFYSA-N
- Catalogue number
- GC65905
- Brand
- GLPBIO
Computed properties PubChem CID 155547374 · XLogP 1.8 · TPSA 132 Ų · H-bond donors 4
- XLogP
- 1.8
- TPSA
- 132 Ų
- H-bond donors
- 4
- H-bond acceptors
- 9
- Rotatable bonds
- 6
- Heavy atoms
- 29
SMILES C1=CC(=C(C=C1C2=CC=C(N2)C(=O)N[C@@H](CN)C3=NC(=CS3)CO)F)C(F)(F)F
Computed descriptors from PubChem (CID 155547374), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il