GC65903
NBD-14270
Also known as N-[(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-3-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]-1H-pyrrole-2-carboxamide
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses· NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity· NBD-14270 shows low cytotoxicity (CC50>100 μM)
ChemicalCAS2411819-82-2MW425.43FormulaC18H18F3N5O2S
- CAS number
- 2411819-82-2
- Molecular weight
- 425.43
- Formula
- C18H18F3N5O2S
- Solubility
- DMSO ： 100 mg/mL (235·06 mM; Need ultrasonic)
- InChIKey
- BILBXEUAJZPBIW-AWEZNQCLSA-N
- Catalogue number
- GC65903
- Brand
- GLPBIO
Computed properties PubChem CID 155519544 · XLogP 1 · TPSA 145 Ų · H-bond donors 4
- XLogP
- 1
- TPSA
- 145 Ų
- H-bond donors
- 4
- H-bond acceptors
- 9
- Rotatable bonds
- 6
- Heavy atoms
- 29
SMILES CC1=C(NC(=C1)C2=NC=C(C=C2)C(F)(F)F)C(=O)N[C@@H](CN)C3=NC=C(S3)CO
Computed descriptors from PubChem (CID 155519544), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il