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Chemical structure of ABN401

GC65894

ABN401

Also known as 4-[5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrimidin-2-yl]-2-[[5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazin-3-yl]methyl]morpholine

ABN401 is a highly potent and selective ATP-competitive c-MET inhibitor with an IC50 value of 10 nM· ABN401 has cytotoxic activity against MET-addicted cancer cells· ABN401 can inhibit c-MET phosphorylation in tumor tissues· ABN401 can be used for researching anticancer

ChemicalCAS2242563-15-9MW566.66FormulaC29H34N12O
CAS number
2242563-15-9
Molecular weight
566.66
Formula
C29H34N12O
InChIKey
PQJGYYZYYMVBDF-UHFFFAOYSA-N
Catalogue number
GC65894
Brand
GLPBIO
Computed properties PubChem CID 118364782 · XLogP 0.9 · TPSA 119 Ų · H-bond donors 0
XLogP
0.9
TPSA
119 Ų
H-bond donors
0
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
42

SMILES CN1CCN(CC1)CC2=CC=C(C=C2)C3=CN=C(N=C3)N4CCOC(C4)CN5C6=NC(=CN=C6N=N5)C7=CN(N=C7)C

Computed descriptors from PubChem (CID 118364782), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.