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Chemical structure of ABM-14

GC62391

ABM-14

Also known as 4-[3-[4-(4-hydroxyphenyl)phenyl]-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile

ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC· ABM-14 binds to a ligand for VHL via linker to form ARCC-4 to degrade AR

ChemicalCAS1973408-76-2MW481.49FormulaC25H18F3N3O2S
CAS number
1973408-76-2
Molecular weight
481.49
Formula
C25H18F3N3O2S
InChIKey
WVKLCXDKHAOSGV-UHFFFAOYSA-N
Catalogue number
GC62391
Brand
GLPBIO
Computed properties PubChem CID 122423026 · XLogP 5.5 · TPSA 99.7 Ų · H-bond donors 1
XLogP
5.5
TPSA
99.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
34

SMILES CC1(C(=O)N(C(=S)N1C2=CC=C(C=C2)C3=CC=C(C=C3)O)C4=CC(=C(C=C4)C#N)C(F)(F)F)C

Computed descriptors from PubChem (CID 122423026), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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