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Chemical structure of BMT-090605 hydrochloride

GC65872

BMT-090605 hydrochloride

Also known as 8-[(2S)-2-amino-4-methylpentoxy]-4,6-dimethyl-5-oxobenzo[c][2,7]naphthyridine-9-carbonitrile;hydrochloride

BMT-090605 hydrochloride is a potent, selective the adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 value of 0·6 nM· BMT-090605 hydrochloride shows antinociceptive activity· BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50 values of 45 nM and 60 nM, respectively· BMT-090605 hydrochloride can be used for the research of neuropathic pain

ChemicalCAS2231664-45-0MW400.9FormulaC21H25ClN4O2
CAS number
2231664-45-0
Molecular weight
400.9
Formula
C21H25ClN4O2
Solubility
DMSO : 31·25 mg/mL (77·95 mM; ultrasonic and warming and heat to 60°C)
InChIKey
JURQHVYCFKMNRC-RSAXXLAASA-N
Catalogue number
GC65872
Brand
GLPBIO
Computed properties PubChem CID 135392527 · TPSA 92.2 Ų · H-bond donors 2 · H-bond acceptors 5
TPSA
92.2 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
28

SMILES CC1=NC=CC2=C1C(=O)N(C3=C2C=C(C(=C3)OC[C@H](CC(C)C)N)C#N)C.Cl

Computed descriptors from PubChem (CID 135392527), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.