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Chemical structure of eIF4A3-IN-2

GC65540

eIF4A3-IN-2

Also known as (4-bromophenyl)-[(2S)-4-(6-bromopyrazolo[1,5-a]pyridine-3-carbonyl)-2-(4-chlorophenyl)piperazin-1-yl]methanone

eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM

ChemicalCAS2095677-20-4MW602.7FormulaC25H19Br2ClN4O2
CAS number
2095677-20-4
Molecular weight
602.7
Formula
C25H19Br2ClN4O2
Solubility
DMSO ： 100 mg/mL (165·92 mM; Need ultrasonic)
InChIKey
WKKAVTNXNVPCCN-HSZRJFAPSA-N
Catalogue number
GC65540
Brand
GLPBIO
Computed properties PubChem CID 131953885 · XLogP 5 · TPSA 57.9 Ų · H-bond donors 0
XLogP
5
TPSA
57.9 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
34

SMILES C1CN([C@H](CN1C(=O)C2=C3C=CC(=CN3N=C2)Br)C4=CC=C(C=C4)Cl)C(=O)C5=CC=C(C=C5)Br

Computed descriptors from PubChem (CID 131953885), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.