GC65477
(Rac)-CFT7455
Also known as 3-[6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-2-oxobenzo[cd]indol-1-yl]piperidine-2,6-dione
(Rac)-CFT7455 is a zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) degrader, acting via the ubiquitin proteasome pathway, with a GI50 of 0·05 nM for NCIH929·1 cells· (Rac)-CFT7455 is the racemic isomer of CFT7455 which is a IKZF1/IKZF3 degrader with anticancer activity
ChemicalCAS2504233-68-3MW469.53FormulaC28H27N3O4
- CAS number
- 2504233-68-3
- Molecular weight
- 469.53
- Formula
- C28H27N3O4
- Solubility
- DMSO ： 62·5 mg/mL (133·11 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- MUKCJOOKCZSQNW-UHFFFAOYSA-N
- Catalogue number
- GC65477
- Brand
- GLPBIO
Computed properties PubChem CID 155194819 · XLogP 2.9 · TPSA 79 Ų · H-bond donors 1
- XLogP
- 2.9
- TPSA
- 79 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 35
SMILES C1CC(=O)NC(=O)C1N2C3=C4C(=C(C=C3)CC5=CC=C(C=C5)CN6CCOCC6)C=CC=C4C2=O
Computed descriptors from PubChem (CID 155194819), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il