Loading...
Chemical structure of Praliciguat

GC65449

Praliciguat

Also known as 1,1,1,3,3,3-hexafluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]amino]methyl]propan-2-ol

Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator

ChemicalCAS1628730-49-3MW534.36FormulaC21H14F8N6O2
CAS number
1628730-49-3
Molecular weight
534.36
Formula
C21H14F8N6O2
Solubility
DMSO ： 250 mg/mL (467·85 mM; Need ultrasonic)
InChIKey
CYSJNTQNMDWAJV-UHFFFAOYSA-N
Catalogue number
GC65449
Brand
GLPBIO
Computed properties PubChem CID 86269973 · XLogP 3.9 · TPSA 102 Ų · H-bond donors 2
XLogP
3.9
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
15
Rotatable bonds
7
Heavy atoms
37

SMILES C1=CC=C(C(=C1)CN2C(=CC(=N2)C3=NC=C(C(=N3)NCC(C(F)(F)F)(C(F)(F)F)O)F)C4=NOC=C4)F

Computed descriptors from PubChem (CID 86269973), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.