Loading...
Chemical structure of TK05

GC65438

TK05

Also known as 5-[5-[4-chloro-N-(cyclopropylmethyl)anilino]pyridine-2-carbonyl]-2-(4-methoxybenzoyl)benzoic acid

TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM

ChemicalCAS1245734-61-5MW540.99FormulaC31H25ClN2O5
CAS number
1245734-61-5
Molecular weight
540.99
Formula
C31H25ClN2O5
Solubility
DMSO ： ≥ 100 mg/mL (184·85 mM)
InChIKey
GRDDFJXOEAJYCT-UHFFFAOYSA-N
Catalogue number
GC65438
Brand
GLPBIO
Computed properties PubChem CID 53385780 · XLogP 6.4 · TPSA 96.8 Ų · H-bond donors 1
XLogP
6.4
TPSA
96.8 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
39

SMILES COC1=CC=C(C=C1)C(=O)C2=C(C=C(C=C2)C(=O)C3=NC=C(C=C3)N(CC4CC4)C5=CC=C(C=C5)Cl)C(=O)O

Computed descriptors from PubChem (CID 53385780), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.