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Chemical structure of LV-320

GC65432

LV-320

Also known as 3-[[4-[(E)-2-(7-chloroquinolin-4-yl)ethenyl]phenyl]-(2-phenylethylsulfanyl)methyl]sulfanylpropanoic acid

LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24·5??M and a Kd of 16??M· LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo

ChemicalCAS2449093-46-1MW520.11FormulaC29H26ClNO2S2
CAS number
2449093-46-1
Molecular weight
520.11
Formula
C29H26ClNO2S2
Solubility
DMSO : 135 mg/mL (259·56 mM; Need ultrasonic)
InChIKey
PHENTWJNXGESKT-RMKNXTFCSA-N
Catalogue number
GC65432
Brand
GLPBIO
Computed properties PubChem CID 134817239 · XLogP 7.8 · TPSA 101 Ų · H-bond donors 1
XLogP
7.8
TPSA
101 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
11
Heavy atoms
35

SMILES C1=CC=C(C=C1)CCSC(C2=CC=C(C=C2)/C=C/C3=C4C=CC(=CC4=NC=C3)Cl)SCCC(=O)O

Computed descriptors from PubChem (CID 134817239), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.