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Chemical structure of Auglurant

GC65389

Auglurant

Also known as N-(5-fluoro-2-pyridinyl)-6-methyl-4-pyrimidin-5-yloxypyridine-2-carboxamide

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human)

ChemicalCAS1396337-04-4MW325.3FormulaC16H12FN5O2
CAS number
1396337-04-4
Molecular weight
325.3
Formula
C16H12FN5O2
Solubility
DMSO ： 22·73 mg/mL (69·87 mM; Need ultrasonic)
InChIKey
RBAHIIPVJVMACF-UHFFFAOYSA-N
Catalogue number
GC65389
Brand
GLPBIO
Computed properties PubChem CID 60168069 · XLogP 1.6 · TPSA 89.9 Ų · H-bond donors 1
XLogP
1.6
TPSA
89.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
24

SMILES CC1=CC(=CC(=N1)C(=O)NC2=NC=C(C=C2)F)OC3=CN=CN=C3

Computed descriptors from PubChem (CID 60168069), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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