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Chemical structure of Atuzabrutinib

GC70685

Atuzabrutinib

Also known as (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile

Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor

ChemicalCAS1581714-49-9MW539.6FormulaC30H30FN7O2
CAS number
1581714-49-9
Molecular weight
539.6
Formula
C30H30FN7O2
Solubility
DMSO ： 100 mg/mL (185·32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
KZMQPYCXSAGLTB-ZWUNQBBJSA-N
Catalogue number
GC70685
Brand
GLPBIO
Computed properties PubChem CID 73438222 · XLogP 5.1 · TPSA 123 Ų · H-bond donors 1
XLogP
5.1
TPSA
123 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
40

SMILES CC(C)(C)/C=C(\C#N)/C(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=C(C=C(C=C4)OC5=CC=CC=C5)F)N

Computed descriptors from PubChem (CID 73438222), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.