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Chemical structure of MLT-748

GC65301

MLT-748

Also known as 1-[2-chloro-7-[(1R,2R)-1,2-dimethoxypropyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(triazol-2-yl)-3-pyridinyl]urea

MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM

ChemicalCAS1832578-30-9MW492.32FormulaC19H19Cl2N9O3
CAS number
1832578-30-9
Molecular weight
492.32
Formula
C19H19Cl2N9O3
Solubility
DMSO ： 200 mg/mL (406·24 mM; Need ultrasonic)
InChIKey
XKQLNDPUQSZBJW-QGHHPUGFSA-N
Catalogue number
GC65301
Brand
GLPBIO
Computed properties PubChem CID 129072285 · XLogP 1.7 · TPSA 133 Ų · H-bond donors 2
XLogP
1.7
TPSA
133 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
33

SMILES C[C@H]([C@@H](C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)N4N=CC=N4)Cl)OC)OC

Computed descriptors from PubChem (CID 129072285), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.