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Chemical structure of MLT-231

GC62611

MLT-231

Also known as 1-[2-chloro-7-[(3S,5S)-3,5-dimethylmorpholin-4-yl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)-4-pyridinyl]urea

MLT-231 is a potent, highly selective allosteric MALT1 Inhibitor with an IC50 of 9 nM· MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM· MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse

ChemicalCAS2682102-10-7MW469.85FormulaC19H19ClF3N7O2
CAS number
2682102-10-7
Molecular weight
469.85
Formula
C19H19ClF3N7O2
Solubility
DMSO ： 110 mg/mL (234·12 mM; Need ultrasonic)
InChIKey
BFPCFGGFGQMJQG-QWRGUYRKSA-N
Catalogue number
GC62611
Brand
GLPBIO
Computed properties PubChem CID 146680905 · XLogP 2.6 · TPSA 96.7 Ų · H-bond donors 2
XLogP
2.6
TPSA
96.7 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
32

SMILES C[C@H]1COC[C@@H](N1C2=C(C=NC3=CC(=NN32)Cl)NC(=O)NC4=CC(=NC=C4)C(F)(F)F)C

Computed descriptors from PubChem (CID 146680905), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.