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Chemical structure of ZL0454

GC65204

ZL0454

Also known as 4-[(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-cyclopentylbenzenesulfonamide

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2

ChemicalCAS2229042-77-5MW374.46FormulaC18H22N4O3S
CAS number
2229042-77-5
Molecular weight
374.46
Formula
C18H22N4O3S
Solubility
DMSO : 50 mg/mL (133·53 mM; Need ultrasonic)
InChIKey
IRKMSULWLDLTIK-UHFFFAOYSA-N
Catalogue number
GC65204
Brand
GLPBIO
Computed properties PubChem CID 137285009 · XLogP 3.3 · TPSA 126 Ų · H-bond donors 3
XLogP
3.3
TPSA
126 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
26

SMILES CC1=CC(=C(C=C1O)N)N=NC2=CC=C(C=C2)S(=O)(=O)NC3CCCC3

Computed descriptors from PubChem (CID 137285009), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.