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Chemical structure of ZL0590

GC64529

ZL0590

Also known as 1-[4-[(2S)-2-(morpholin-4-ylmethyl)pyrrolidin-1-yl]sulfonylphenyl]-3-[4-(trifluoromethyl)phenyl]urea

ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1

ChemicalCAS2230496-99-6MW512.55FormulaC23H27F3N4O4S
CAS number
2230496-99-6
Molecular weight
512.55
Formula
C23H27F3N4O4S
Solubility
DMSO : 100 mg/mL (195·10 mM; Need ultrasonic)
InChIKey
ZPMULUKHFNMJPF-FQEVSTJZSA-N
Catalogue number
GC64529
Brand
GLPBIO
Computed properties PubChem CID 135144027 · XLogP 2.7 · TPSA 99.4 Ų · H-bond donors 2
XLogP
2.7
TPSA
99.4 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
35

SMILES C1C[C@H](N(C1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C(F)(F)F)CN4CCOCC4

Computed descriptors from PubChem (CID 135144027), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.