GC65200
Nevanimibe hydrochloride
Also known as 1-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]-3-[2,6-di(propan-2-yl)phenyl]urea;hydrochloride
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM· Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM· Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer
ChemicalCAS133825-81-7MW458.08FormulaC27H40ClN3O
- CAS number
- 133825-81-7
- Molecular weight
- 458.08
- Formula
- C27H40ClN3O
- Solubility
- DMSO ： 41·67 mg/mL (90·97 mM; Need ultrasonic)|Water ： ＜ 0·1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
- InChIKey
- SDOOGTHIDFZUNM-UHFFFAOYSA-N
- Catalogue number
- GC65200
- Brand
- GLPBIO
Computed properties PubChem CID 131678 · TPSA 44.4 Ų · H-bond donors 3 · H-bond acceptors 2
- TPSA
- 44.4 Ų
- H-bond donors
- 3
- H-bond acceptors
- 2
- Rotatable bonds
- 7
- Heavy atoms
- 32
SMILES CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NCC2(CCCC2)C3=CC=C(C=C3)N(C)C.Cl
Computed descriptors from PubChem (CID 131678), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il