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Chemical structure of Neutrophil elastase inhibitor 5

GC75569

Neutrophil elastase inhibitor 5

Also known as (2S)-2-[[3-[(2-hydroxynaphthalen-1-yl)diazenyl]pyridine-2-carbonyl]amino]-2-phenylacetic acid

Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC50 values of 4·91 μM and 20·69 μM, respectively

ChemicalCAS3020696-44-7MW426.42FormulaC24H18N4O4
CAS number
3020696-44-7
Molecular weight
426.42
Formula
C24H18N4O4
Solubility
DMSO: 12·5 mg/mL (29·31 mM; ultrasonic and warming and heat to 60°C)
InChIKey
SYTDKDNZPVIALG-FQEVSTJZSA-N
Catalogue number
GC75569
Brand
GLPBIO
Computed properties PubChem CID 169450431 · XLogP 4.4 · TPSA 124 Ų · H-bond donors 3
XLogP
4.4
TPSA
124 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
32

SMILES C1=CC=C(C=C1)[C@@H](C(=O)O)NC(=O)C2=C(C=CC=N2)N=NC3=C(C=CC4=CC=CC=C43)O

Computed descriptors from PubChem (CID 169450431), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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