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Chemical structure of RTI-7470-44

GC65172

RTI-7470-44

Also known as 2-[[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)-2-pyridinyl]sulfanyl]-N-pyrimidin-2-ylacetamide

RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8·4 nM and a Ki value of 0·3 nM

ChemicalCAS825658-63-7MW449.84FormulaC19H11ClF3N5OS
CAS number
825658-63-7
Molecular weight
449.84
Formula
C19H11ClF3N5OS
Solubility
DMSO ： 20·83 mg/mL (46·31 mM; ultrasonic and warming and heat to 60°C)
InChIKey
WHNQNKYKDSLDKM-UHFFFAOYSA-N
Catalogue number
GC65172
Brand
GLPBIO
Computed properties PubChem CID 2225078 · XLogP 4.1 · TPSA 117 Ų · H-bond donors 1
XLogP
4.1
TPSA
117 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
30

SMILES C1=CN=C(N=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)Cl)C(F)(F)F)C#N

Computed descriptors from PubChem (CID 2225078), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.