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Chemical structure of RTC-5

GC37568

RTC-5

Also known as N-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(trifluoromethoxy)benzenesulfonamide

RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency· RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling

ChemicalCAS1423077-49-9MW510.96FormulaC24H22ClF3N2O3S
CAS number
1423077-49-9
Molecular weight
510.96
Formula
C24H22ClF3N2O3S
Solubility
DMSO： 15 mg/mL (29·36 mM)
InChIKey
QYOJMNDDVVEPFN-UHFFFAOYSA-N
Catalogue number
GC37568
Brand
GLPBIO
Computed properties PubChem CID 71263344 · XLogP 7 · TPSA 67 Ų · H-bond donors 1
XLogP
7
TPSA
67 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
34

SMILES C1CC2=CC=CC=C2N(C3=C1C=CC(=C3)Cl)CCCNS(=O)(=O)C4=CC=C(C=C4)OC(F)(F)F

Computed descriptors from PubChem (CID 71263344), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.