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Chemical structure of VU0529331

GC65125

VU0529331

Also known as [2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone

VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) activator, with EC50s of 5·1 ?M and 5·2 ?M for GIRK2 and GIRK1/2 in HEK293 cells, respectively, also effective on GIRK4 homomeric channel

ChemicalCAS1286725-49-2MW384.43FormulaC22H20N6O
CAS number
1286725-49-2
Molecular weight
384.43
Formula
C22H20N6O
Solubility
DMSO ： 5 mg/mL (13·01 mM; Need ultrasonic and warming)
InChIKey
KKICJSSCAYMJOA-UHFFFAOYSA-N
Catalogue number
GC65125
Brand
GLPBIO
Computed properties PubChem CID 52417637 · XLogP 2.1 · TPSA 68.8 Ų · H-bond donors 0
XLogP
2.1
TPSA
68.8 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
29

SMILES CC1=C(C=C(C=C1)N2C(=C3CN(CC3=N2)C(=O)C4=NC=CN=C4)N5C=CC=C5)C

Computed descriptors from PubChem (CID 52417637), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.