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Chemical structure of MC-VA-PABC-MMAE

GC65109

MC-VA-PABC-MMAE

Also known as [4-[[(2S)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]propanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate

MC-VA-PABC-MMAE is a drug-linker conjugate for ADC· MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE

ChemicalCAS1818864-51-5MW1230.53FormulaC65H99N9O14
CAS number
1818864-51-5
Molecular weight
1230.53
Formula
C65H99N9O14
Solubility
DMSO ： 100 mg/mL (81·27 mM; Need ultrasonic)
InChIKey
IQZWSFIVBFLXDH-RKMHKBIWSA-N
Catalogue number
GC65109
Brand
GLPBIO
Computed properties PubChem CID 164886612 · XLogP 5.8 · TPSA 292 Ų · H-bond donors 6
XLogP
5.8
TPSA
292 Ų
H-bond donors
6
H-bond acceptors
14
Rotatable bonds
35
Heavy atoms
88

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O

Computed descriptors from PubChem (CID 164886612), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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