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Chemical structure of LysRs-IN-2

GC65058

LysRs-IN-2

Also known as N-[(4,4-difluoro-1-hydroxycyclohexyl)methyl]-6-fluoro-4-oxochromene-2-carboxamide

LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0·015 μM and 0·13 μM for Plasmodium falciparum lysyl-tRNA synthetase (PfKRS) and Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS), respectively

ChemicalCAS2170696-76-9MW355.31FormulaC17H16F3NO4
CAS number
2170696-76-9
Molecular weight
355.31
Formula
C17H16F3NO4
Solubility
DMSO ： ≥ 60 mg/mL (168·87 mM)
InChIKey
PJBRCGHQNUWERQ-UHFFFAOYSA-N
Catalogue number
GC65058
Brand
GLPBIO
Computed properties PubChem CID 134158252 · XLogP 2.2 · TPSA 75.6 Ų · H-bond donors 2
XLogP
2.2
TPSA
75.6 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
25

SMILES C1CC(CCC1(CNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)F)O)(F)F

Computed descriptors from PubChem (CID 134158252), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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