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Chemical structure of Lys01 trihydrochloride

GC19237

Lys01 trihydrochloride

Also known as N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine;trihydrochloride

Lys01 trihydrochloride (Lys01 trihydrochloride) is a novel lysosomal autophagy inhibitor with IC50 values of 3·6, 3·8, 6 and 7·9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay

ChemicalCAS1391426-24-6MW549.75FormulaC23H26Cl5N5
CAS number
1391426-24-6
Molecular weight
549.75
Formula
C23H26Cl5N5
Solubility
DMSO : 75 mg/mL (136·43 mM);Water : 6·4 mg/mL (11·64 mM)
InChIKey
JTUYDBHQGOZPQQ-UHFFFAOYSA-N
Catalogue number
GC19237
Brand
GLPBIO
Computed properties PubChem CID 70673566 · TPSA 53.1 Ų · H-bond donors 5 · H-bond acceptors 5
TPSA
53.1 Ų
H-bond donors
5
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
33

SMILES CN(CCNC1=C2C=CC(=CC2=NC=C1)Cl)CCNC3=C4C=CC(=CC4=NC=C3)Cl.Cl.Cl.Cl

Computed descriptors from PubChem (CID 70673566), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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