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Chemical structure of MM-589 TFA

GC65037

MM-589 TFA

Also known as N-[(3R,6S,9S,12R)-6-ethyl-12-methyl-9-[3-[(N'-methylcarbamimidoyl)amino]propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetrazacyclotetradec-12-yl]-2-methylpropanamide;2,2,2-trifluoroacetic acid

MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction· MM-589 binds to WDR5 with an IC50 of 0·90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12·7 nM

ChemicalCAS2097887-21-1MW686.72FormulaC30H45F3N8O7
CAS number
2097887-21-1
Molecular weight
686.72
Formula
C30H45F3N8O7
Solubility
DMSO ： 25 mg/mL (36·40 mM; ultrasonic and warming and heat to 60°C)
InChIKey
NARXNZHWAWPJIY-HTCBAMNXSA-N
Catalogue number
GC65037
Brand
GLPBIO
Computed properties PubChem CID 132585206 · TPSA 233 Ų · H-bond donors 8 · H-bond acceptors 11
TPSA
233 Ų
H-bond donors
8
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
48

SMILES CC[C@H]1C(=O)N[C@@H](C(=O)NCC[C@@](C(=O)N[C@H](C(=O)N1)CCCNC(=NC)N)(C)NC(=O)C(C)C)C2=CC=CC=C2.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 132585206), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.